منابع مشابه
Tumour-induced osteomalacia: a curable condition
Osteomalacia is a condition characterised by failure of bone mineralisation. While abnormalities of vitamin D supply, metabolism or action are the most common and well-known causes, chronic phosphate deficiency, due to either insufficient input (intake or absorption) or renal losses are also important causes of rickets or osteomalacia.1 Hypophosphataemia also commonly co-exists with vitamin D d...
متن کاملTumour-induced osteomalacia: a literature review and a case report.
Tumour-induced osteomalacia (TIO) is a rare paraneoplastic syndrome characterised by severe hypophosphataemia and osteomalacia, with renal phosphate wasting that occurs in association with tumour. The epidemiology likewise aetiology is not known. The clinical presentation of TIO includes bone fractures, bone and muscular pains, and sometimes height and weight loss. TIO may be associated with me...
متن کاملAn aggressive bone tumour: osteogenic osteomalacia.
A 58-year-old Caucasian man presented to his general practitioner with over 1 year of severe back pain and was discovered to have very low vitamin D3 levels (<10 nmol/l). Alkaline phosphatase was elevated at 160 U/l , calcium levels decreased to a low of 2.06 mmol/l and phosphate to 0.76 mmol/l. He was prescribed vitamin D supplements and levels began to normalise, but developed increasing pain...
متن کاملTumor-induced osteomalacia.
Tumor-induced osteomalacia (TIO) is a rare paraneoplastic form of renal phosphate wasting that results in severe hypophosphatemia, a defect in vitamin D metabolism, and osteomalacia. This debilitating disorder is illustrated by the clinical presentation of a 55-year-old woman with progressive fatigue, weakness, and muscle and bone pain with fractures. After a protracted clinical course and exte...
متن کاملCadmium-induced osteomalacia.
The detailed study of a battery plate maker, who had worked with cadmium for 36 years, showed that proteinuria, typical of renal tubular dysfunction, had been observed for 25 years and during the last 12 years of his life the patient had suffered increasing disability from gross bone disease. Several bone biopsies and detailed metabolic studies showed typical severe osteomalacia, which responde...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Case Reports
سال: 2012
ISSN: 1757-790X
DOI: 10.1136/bcr.03.2012.5975